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Additionally they are tested separately and regulated to ensure they provide a fair result.Pragmatic is a software development company that provides a variety of casino games on online gambling platforms. Pragmatic's iGaming software is used by the top operators and land based casinos. The company offers front-end site design tools, analysis tools and promotions, marketing security payment systems, customer service and bug-reporting. Additionally, the company provides its players a safe and secure environment with high-quality graphics as well as gaming.The company has a vast library of games that are available for demo play. This lets players try new games without having to sign up or log in. These games are played instantly and provide a real casino feel. These games are available on mobile, desktop and tablet devices.The company is known for its unique rewards systems and mobile-first strategy. 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Some of these games include bonus rounds that allow players to earn free spins.The company's latest release Gates of Olympus takes players to the realm of the ancient Greek gods in which Zeus is in charge of the action. This slot game with high volatility features the Pay Anywhere option that pays players if they get 8 or more identical symbols on the reels. It also has a lucrative Free Spins feature with multipliers that can go up to 500x the bet.Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and included participants from different geographical regions. This type of heterogeneity is required for practical trials to be valid and also helps reduce bias in the results. 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Other notable titles include Wolf Gold and Chilli Heat.Pragmatic trials seek to replicate real-world situations and have the highest external validity. They are typically commissioned by policymakers and practitioners in order to guide their decisions. They are also a good method to determine the causality between an intervention and its outcomes. However, they should not be used as a substitute for explanatory trials.The pragmatism idea is controversial, and there are questions about whether pragmatic trials can be used to replace explanation tests or if they are an addition to them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which support a physiological hypothesis or clinical hypothesis, and pragmatic trials, which inform the decision-making process for policy and practice. They also proposed the framework for pragmatic trials, which they called PRECIS.2 This tool was designed to define the features of a pragmatic trial, including the recruitment process, the design and delivery of the intervention, and the follow-up.The number of pragmatic trials is growing. A recent Medline search using the terms naturalistic and pragmatic, limited to controlled trials that are randomized (RCTs), yielded 34 articles, as shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to note that the majority of these studies were conducted in primary-care settings.
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