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Some of these games include a bonus game that allows players to win free spins.Gates of Olympus, a new game from the company, transports players into the realm of the ancient Greek gods where Zeus supervises all the action. This slot game with high volatility features the Pay Anywhere option that rewards players when they land 8 or more identical symbols on the reels. This game also comes with an Free Spins bonus with multipliers that can be as high as 500x your stake.A pragmatic study that involves different investigators and participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity, that is crucial for a pragmatic trial to be valid and lessen the chance of bias, is also necessary. However, too much heterogeneity can result in problems with the design of the trial.Pragmatic Play is one of the biggest players on the live casino market offers a variety of classic table games such as Blackjack and Roulette. 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However, they should not, be used to replace the need for explanation studies.The idea of pragmatism is controversial and there are doubts about whether pragmatic trials should replace tests for explanations or if they should be a complement to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which confirm the validity of a clinical or physiological hypothesis and pragmatic trials, which inform the practice and policy decisions. They also suggested an approach to pragmatic trials, dubbed PRECIS.2 This tool sought to define the features of a practical trial that include the recruitment process, the design and implementation of the intervention, as well as follow-up.The number of pragmatic trials is increasing. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to keep in mind that the majority of these studies were conducted in primary care settings.