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The BIOFIRE System and Your Immune SystemThe BIOFIRE System offers syndromic testing for infectious illnesses, allowing healthcare professionals to select the appropriate test first time. Patients benefit from faster diagnosis and more targeted therapy. Clinicians benefit from better antibiotic stewardship. Labs save money while increasing efficiency.The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL) and endotracheal lavage and bronchoalveolar slurries (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in one hour.RespiratoryThe burning of biomass, including wood, plants and other organic materials creates gaseous pollution and fine particles that adversely affect the respiratory system. Climate change may make it more difficult to reverse the negative impacts of forest fires on human health.In the United States, wildfire smoke has been associated with hospitalizations for respiratory diseases like asthma, COPD and lung cancer. This type of air pollution also increases the risk of cardiovascular disease and is a major contributor to the burden of disease in the most vulnerable populations.In the COVID-19 pandemic, a number of communities were exposed to harmful levels of air pollution resulting from wildfires. The response to public health has been limited to a public education campaign on the management of symptoms. This knowledge gap is alarming due to the fact that smoking cigarettes and other sources of poor quality air can lead to health issues.Researchers are now evaluating the best way to safeguard public's health during future events of this kind. NIH is a research institution that studies this crucial public health issue through the BLUE CORAL and FIRE CORAL studies.For the first time, a prospective study will examine the long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL is seeking adult participants hospitalized for the COVID-19 index episode who have a fluency in English or Spanish and are not pregnant. The FIRE CORAL protocol includes a series of in-person assessments objectively measuring lung function tests and pulmonary imaging and functional assessment.Smoke and other particles can cause or worsen respiratory conditions such as emphysema, COPD, and pneumonia. A variety of steps can be taken to avoid or lessen the negative health effects of exposure to smoke, including avoidance of outdoor activities whenever possible and using the EPA's "N95" mask, which is designed to trap fine particles.Smoking can cause irritation to the throat, eyes and nose. To lessen the effects the lungs need to be flushed with plenty of water and taking medicines which reduce inflammation, like corticosteroids.BloodstreamYour bloodstream is on the front lines of fighting off germs that enter your body. Fireplaces And Stove are special cells, act as a call center your fire department. They collect antigens from bacteria and release proteins to alert other white cells to fight off them. Circulating total white blood cells, differentials, and band cells were elevated following firefighters' fire-fighting shifts, compared with levels after strenuous physical exertion without fire-fighting.SkinDermatologists were concerned that the smoke and ash that resulted from the California wildfires could have an adverse effect on the skin of those who were exposed to these substances. Maria Wei is a graduate student from University of California, Irvine. She investigates how the extreme pollution from wildfires impacts the skin. Her research was published in Scientific Reports on April 22nd.Wei's study shows that the temperature changes of the skin dependent on the amount of time that the body is exposed. It can take as long as two hours for the skin to reach its flash point--the place where it begins to burn and then turns to ash. It is important to avoid staying near a fire pit or campfire and wear protective clothing if you're going outside on a hot or humid day.Forest fires will continue to happen, despite the precautions taken to stop wildfire pollution. Wei is predicting that the number of people suffering the effects of wildfires will rise as climate change causes more and more forests to burn. That means more people will be required to wear hats, long sleeves, and thick moisturizers.The air pollution from wildfires can exacerbate atopic skin dermatitis, which causes itchy skin for many people. The particles in smoke can clog up pores and cause atopic skin to become worse.Atopic dermatitis can make people more sensitive towards UV light. This can be made worse by smoke from wildfires. This can cause people to be more likely to go to tanning salons, and may cause the skin to get darker with less protection than they need to.While a fire and ice facial can help lessen the effects of atopic dermatitis, it is not safe for anyone with an open wound or rash on their face. This treatment is not recommended for those with active acne or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' top membership MedSpa, is an intensive, results-driven facial that bridges the gap between a mild facial and a peel, without requiring any downtime. It's designed to rejuvenate skin, improve rosacea and decrease acne scarring and fine lines and encourage cellular regeneration. It's a fantastic treatment that will give you radiant skin.InfectionsThe human body is a complicated system of organs and tissues that work together to guard us against infection. Infections are caused by microscopic microorganisms like parasites, viruses, bacteria and fungi that infect healthy cells and cause them to replicate beyond control. Your immune system can react by exhibiting symptoms of illness. These symptoms can include anything from a swollen or achy nose to a stomach upset however, they may also include a fever that is high or swollen glands. You may also experience an itchy rash. The type of infection and its location can affect your symptoms.Infections can spread in a variety of ways but the most prevalent are transmitted from person to person by droppings that hang in the air after sneezing or coughing. Bacterial diseases such as tuberculosis and strep throat meningococcal disease, and Legionnaires disease spread in this manner, as do certain viral infections such as the common cold and influenza. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) like gonorrhea or chlamydia are spread through direct contact with affected tissues or mucous surfaces or indirectly by contaminated surfaces. Certain bacterial infections are transmitted by insects, such as ticks, fleas, or mosquitoes.Some parasites and viruses are small enough to get into your bloodstream and infect your cells, which leads to serious illnesses like the common cold and AIDS. Fungi can cause skin conditions like athlete's feet and ringworm and some can affect the respiratory system and the nervous system.The BioFire Panel utilizes our unique FilmArray technology to analyze the sputum and bronchoalveolar fluid samples to provide a complete list of pathogens that are involved in upper respiratory infections. The kit comes with a reagent kit that contains all the chemistry needed to perform reverse transcription, nested multiplex PCR and detection with a single machine. It's an easy-to-use solution to assist clinicians in identifying syndromic patterns and treat patients with a variety of respiratory symptoms. This test has been given an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high complexity laboratories.