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The BIOFIRE System and Your Immune SystemThe BIOFIRE System provides syndromic infectious disease testing, empowering healthcare providers to select the appropriate test the first time. Patients benefit from faster diagnosis and a more specific treatment. Clinicians benefit from improved antibiotic stewardship. Labs gain efficiency and cost savings.The BioFire FilmArray Pneumonia plus panel (PN panel) analyzes native sputum endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes. The panel provides semiquantitative results in about an hour.RespiratoryThe burning of biomass, including plants, wood and other organic materials creates gaseous pollution and fine particles that negatively affect the respiratory system. Climate change may exacerbate the negative effects of forest fires to human health.In the United States wildfire smoke is linked to hospitalizations due to respiratory illnesses like asthma, COPD, and lung cancer. Additionally, this kind of air pollution is a risk factor for cardiovascular disease and a significant contributing factor to the burden of illness among the most vulnerable populations which includes those who are of lower socioeconomic status (SES).During the COVID-19 pandemic, a number of communities were exposed to unhealthy levels of air pollution due to wildfires. The public health response has been limited to a communication campaign regarding symptom management. This lack of knowledge is alarming considering the evidence of potential health risks from continued exposure to smoke and other causes of poor air quality.Researchers are now evaluating the best ways to protect public health in future events similar to this. NIH invests in research on this important public health issue through the BLUE CORAL and FIRE CORAL studies.For the first time, a prospective cohort study will assess long-term outcomes from exposure to smoke from wildfires and other sources. FIRE CORAL is recruiting adult participants who have been hospitalized for COVID-19's index episode who speak English or Spanish and are not pregnant. The FIRE CORAL protocol includes a set of in-person assessments objectively measuring pulmonary function testing and lung imaging, as well as functional assessment.Smoke and other particles can trigger or worsen respiratory problems like emphysema COPD and pneumonia. A variety of steps can be taken to stop or lessen the negative health effects from short-term exposures to smoke, such as avoidance of outdoor activities whenever feasible and wearing the EPA's "N95" mask designed to trap fine particles.Smoking can also cause irritation to the eyes, throat and nose. To reduce the symptoms, drink lots of water, and take medication to reduce inflammation, like corticosteroids.BloodstreamYour bloodstream is at the forefront of fighting germs that invade your body. Dendritic cells are specialized cells that are like the fire department's call center; they take antigens (molecules that trigger an immune response) from invaders and then release proteins that alert other white blood cells to to fight them. The total number of white blood cells, differentials, and band cells increased following firefighters' firefighting tasks, compared to levels after vigorous exercise that did not include firefighting.SkinAs the wildfires in California spewed smoke and dust into the air over the course of winter and fall dermatologists were concerned how that could affect the skin of those exposed to it. Maria Wei is a graduate student from University of California, Irvine. She investigates how the extreme pollution from wildfires affects the skin. Her research was published in Scientific Reports on April 22nd.The study by Wei shows that temperature changes of the skin dependent on the amount of time the body is exposed. It can take as long as two hours for the skin of an individual to reach its "flash point"--the moment at which it begins to burn and then turns to ash. This is why it's crucial to avoid being near an open flame or campfire and why you must wear protective clothing when you are outside during a forest fire or even just a hot day.While it is important to be vigilant against fire-related pollution, there's no way to stop forest fires from happening. Wei predicts that as the climate changes cause forests to burn more, the number of people suffering from wildfires will rise. That means more people will have to wear long sleeves, hats and thick moisturizers.It's also worth knowing that the atopic dermatitis (itchy skin) that many people suffer from can be made worse by wildfire air pollution. She claims that the particles in smoke can clog up pores, making atopic skin worse.Atopic dermatitis may cause people to be more sensitive to UV light. This can be exacerbated by smoke from wildfires. This could lead to people seeking out tanning salons to get tanned with less protection.While a ice and fire facial may reduce the effects of atopic dermatitis, it's not recommended for those with an open wound or rash on their face. This treatment is not recommended for people who have active acne, or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa It's a highly effective result-driven facial that bridges the gap between a mild facial and a peel without requiring any downtime. It's designed to rejuvenate skin, improve rosacea, reduce acne scarring and fine lines and stimulate cellular regeneration. This is a great treatment to give your skin a glowing glow.InfectionsThe human body is made up of a complex set of organs and tissue which work together to protect us against infection. Infections are caused by microscopic microorganisms like viruses, bacteria, parasites and fungus that invade healthy cells and cause them to reproduce beyond control. When this happens your immune system could respond by displaying symptoms of illness. These symptoms could be anything from a snoring nose to an upset stomach and can also include a fever, swollen lymph glands, or an itchy scratch. The severity of your symptoms may be affected by the nature of the infection, its location and even your temperature.Infections can spread in various ways, but they are most often spread through droplets in the air that remain after coughing or sniffling. Bacterial diseases like tuberculosis and strep throat meningococcal diseases and Legionnaires disease spread through this method, along with certain viral infections such as the common cold and influenza. ethanol fires as skin infections or sexually transmitted diseases (STIs) like gonorrhea or chlamydia are spread through direct contact with affected mucous or tissue surfaces, or indirectly through contaminated surfaces. Certain bacterial infections are transmitted by insects such as fleas, ticks, or mosquitoes.The virus and the parasites are small enough to penetrate your bloodstream and infect your cells which leads to serious illnesses like the common cold or AIDS. Fungi can cause skin problems such as ringworm and athlete's foot and some can affect the respiratory system and the nervous system.The BioFire Panel uses our innovative FilmArray Technology to test the sputum and bronchoalveolar fluid samples to provide a complete list of pathogens involved in upper respiratory infections. The kit includes the reagent pouch which stores all the necessary chemicals to perform reverse transcription PCR, multiplex nested PCR and detection with a single device. This is a straightforward solution that helps clinicians identify and treat patients suffering from several respiratory symptoms. The test has been granted an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high complexity labs.