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The BIOFIRE System and Your Immune SystemThe BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to choose the appropriate test the first time. Patients benefit from quicker diagnosis and a more specific treatment. Clinicians benefit from improved antibiotic stewardship. Labs are more efficient and can make cost savings.The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL), endotracheal lavage, and bronchoalveolar liquids (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in one hour.RespiratoryThe burning of biomass, such as plants, wood and other organic materials, produces gaseous pollutants and fine particulates that negatively affect the respiratory system. Climate change could increase the negative impacts of forest fires on the health of humans.In the United States, wildfire smoke has been linked to hospitalizations for respiratory diseases like asthma, COPD and lung cancer. Furthermore, this type of air pollution can be an underlying risk factor for cardiovascular diseases and a major contributing factor to the burden of illness in the most vulnerable populations that include those who are of lower socioeconomic status (SES).During the COVID-19 epidemic, many communities were exposed levels of air pollution due to wildfires. The response to public health has been limited to a communication campaign about managing symptoms. bio-ethanol fires is concerning due to the evidence of possible health hazards from the continued exposure to smoke and other sources of poor air quality.Researchers are now evaluating how to best protect the public's health during any future events of this kind. NIH is a research institution that studies this important public health issue through the BLUE CORAL and FIRE CORAL studies.First time, a prospective study will assess the long-term effects of exposure to smoke from wildfires or other sources. FIRE CORAL is looking for adult participants hospitalized for COVID-19's index episode who are fluent in English or Spanish and are not pregnant. The Fire Coral protocol includes a battery in-person assessments that objectively measure pulmonary function testing lung imaging and functional assessment.Smoke and other particles can cause or worsen respiratory problems such as emphysema, COPD and pneumonia. There are a variety of steps that can be taken to prevent or reduce the adverse health effects of exposure to smoke, such as avoidance of outdoor activities whenever possible and using the EPA's "N95" mask that is designed to trap fine particles.Smoke can also cause irritation to the eyes and throat, and cause an irritated nose. To minimize symptoms, drink lots of fluids and take medication to reduce inflammation, such corticosteroids.BloodstreamThe bloodstream is your first line of defense against germs that invade your system. Dendritic cells, which are specific cells, serve as the call center for your fire department. They are able to collect antigens from germs and release proteins that alert other white cells to fight. Circulating white blood cell counts, differentials and band cells were increased after firefighters' firefighting shifts, as compared to levels after strenuous physical exertion without firefighting.SkinAs the wildfires in California released smoke and dust into the air over the course of fall and winter dermatologists were concerned about how that could affect the skin of people exposed to it. Maria Wei is a graduate student at the University of California, Irvine. She studies how extreme wildfire pollution impacts the skin. Her research was published on April 22 2012 in Scientific Reports.The study by Wei shows that temperature changes of the skin dependent on the amount of time that the body is exposed. It can take up to two hours for the skin to reach its flash point -- the point at which it burns and turns to ash. This is the reason why it's essential to stay away from the campfire or a fire, and why you should wear protective clothing if you are outside during a forest fire or even an extremely hot day.While it's important to be vigilant against wildfire pollution, there is no way to stop forest fires from occurring. Wei predicts that the number of people suffering from the consequences of wildfires will increase as climate change causes more forests to be burned. This means that more people will be required to wear long sleeves, hats and thick moisturizers.The air pollution from wildfires can exacerbate atopic skin dermatitis, which is a condition that causes itchy skin in a lot of people. She says that the particles in smoke can clog pores and cause atopic skin to become worse.Another issue is that atopic dermatitis tends to make people more sensitive to UV light, which can be aggravated by wildfire smoke. This can result in people seeking out tanning salons to tannish with less protection.A fire and ice treatment could help to reduce atopic conditions however it is not recommended for those with an open wound or rash. Patients who suffer from acne are advised to avoid it as well and if you're pregnant or breastfeeding it is recommended to stay clear of this procedure altogether. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa, is an intensive, results-driven facial that bridges the gap between a gentle facial and a peel without having to wait for any downtime. It's designed to rejuvenate the skin, alleviate the appearance of rosacea, reduce acne scarring, reduce lines and wrinkles, and stimulate the renewal of cells. It's an amazing treatment that will give you a radiant glow.InfectionsThe human body is a complex network of organs and tissues that work to guard us against infection. Infections are caused by microscopic organisms like bacteria, viruses, parasites and fungus that infiltrate healthy cells and cause them to replicate out of control. Your immune system may react by exhibiting symptoms of illness. The symptoms could range from a runny nose to a stomach that is upset as well as an increase in fever, swelling of lymph glands or an scratch. The type of infection and the location can impact the symptoms.Infections can be spread in different ways, but most commonly through droplets in the air that remain after a sniff or cough. Bacterial infections like strep throat, tuberculosis, meningococcal disease and Legionnaires disease spread this way, along with some viral infections, such as the common cold and influenza. Some bacterial infections, such as skin infections and sexually transmitted infections (STIs) like gonorrhea or chlamydia, are spread by direct contact with infected tissues or mucous membranes, or through indirect contact with surfaces that are contaminated. Certain infections caused by bacteria are transmitted by insects such as ticks, fleas, or mosquitoes.The parasites, viruses and other microorganisms are tiny enough to enter your bloodstream and infect your cells. This can result in serious illnesses such as the common cold or AIDS. Fungi can trigger skin conditions such as ringworm and athlete's foot and others can infect the respiratory system and the nervous system.The BioFire Panel employs our revolutionary FilmArray Technology to test sputum and bronchoalveolar fluid samples to provide a complete list of pathogens that are involved in upper respiratory infections. The kit comes with a reagent kit that contains all the chemistry needed to perform reverse transcription, nested multiplex PCR and detection in one machine. This is a simple solution that helps clinicians identify and treat patients suffering from a variety respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high complexity labs.