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The BIOFIRE System and Your Immune SystemThe BIOFIRE System provides syndromic infectious disease testing, empowering healthcare professionals to select the most appropriate test, the first time. Patients benefit from faster diagnosis and more targeted therapy. Clinicians benefit from better stewardship of antibiotics. Labs save money and gain efficiency.The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes with semiquantitative results in about an hour.RespiratoryThe burning of biomass (wood plants, trees and other organic materials) produces gaseous pollutants and fine particles that negatively impact the respiratory system. Climate change could exacerbate the negative impacts of forest fires on human health.In the United States wildfire smoke is linked to hospitalizations due to respiratory illnesses like asthma, COPD, and lung cancer. Furthermore, this type of air pollution is an important risk factor for cardiovascular diseases and is a significant contributor to the burden of disease among the most vulnerable populations that include those who are of lower socioeconomic status (SES).In the COVID-19 pandemic, many communities were exposed to unhealthy levels of air pollution resulting from wildfires. The public health response has been limited to a public education campaign about the management of symptoms. This knowledge gap is alarming, considering the evidence that smoking cigarettes and other sources of poor quality air can lead to health problems.Researchers are now evaluating the best ways to protect public health during future events similar to this. NIH is funding research on this crucial public health issue through the BLUE CORAL study as well as its successor, FIRE CORAL.For the first time the study is a prospective cohort study that will evaluate long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL enrolls adults who are hospitalized for COVID-19 index episode and speak English or Spanish, but are not pregnant. The protocol for FIRE CORAL includes a set of tests in-person that objectively measure pulmonary function testing and lung imaging as well as functional assessment.The lungs are especially sensitive to the effects of smoke and other particles because they can trigger or worsen chronic respiratory conditions such as emphysema, asthma and COPD and increase the risk of pneumonia. A number of steps can be taken to prevent or minimize the negative health effects of exposure to smoke, such as abstaining from outdoor activities when it is possible and using the EPA's "N95" mask, which is designed to catch fine particles.Smoking can cause irritation of the throat and eyes, and can cause a runny nose. To lessen the effects the lungs must be flushed with plenty of fluids and taking medications which reduce inflammation, like corticosteroids.BloodstreamThe bloodstream is your first line of defense against germs that enter your system. Dendritic cells are special cells, act as a call center your fire department. They gather antigens from germs and release proteins that alert other white cells to fight. The white blood cell counts, differentials and band cells were increased during firefighters' firefighting shifts, compared with levels following physical exertion without fire-fighting.SkinAs the wildfires in California released smoke and ash into the air this past fall and winter dermatologists were concerned about how it could affect the skin of those who were exposed to it. Maria Wei, a graduate student at University of California, Irvine is researching how extreme pollution from wildfires affects the skin. Her research was published on April 22, 2012 in Scientific Reports.Wei's research has shown that the temperature of the skin changes based on the length of time that the body is exposed to flames. It could take up to two hours for the skin of an individual to reach its "flash point"--the point where it starts to burn and then turn to ash. This is why it's crucial to not stay near a fire or campfire, and why you must wear protective clothing when you are outdoors during a forest fire or even just a hot day.While it's important to be aware of the dangers of wildfire-related pollution, there's no way to stop forest fires from happening. Wei is forecasting that the number of people suffering the effects of wildfires will grow as climate change causes more forests to burn. This means that more people will be required to wear long sleeves, hats and thick moisturizers.It's also worth knowing that atopic dermatitis (itchy skin) which many suffer from is often exacerbated by wildfire air pollution. She claims that the particles in smoke can clog pores which can cause skin irritation.Another issue is the fact that atopic dermatitis can make people more sensitive to UV light, which can be aggravated by wildfire smoke. This can result in people looking for tanning salons and get tanned with less protection.A fire and ice treatment can help reduce atopic skin dermatitis symptoms however it is not advised for anyone who has an open wound or rash. bio-fireplace www.fireplacesandstove.com who suffer from acne are advised to avoid it If you're nursing or pregnant, it is best to steer clear of this procedure altogether. The IS Clinical Fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges between a mild facelift and a peel, but without the need for time off. It's designed to rejuvenate the skin, alleviate the appearance of rosacea, reduce acne scarring, reduce wrinkles, and promote the renewal of cells. It's an incredible treatment that will give you an energizing glow.InfectionsThe human body is a multi-faceted network of organs and tissues that work to shield us from infection. Infections can be caused by microorganisms, such as parasites, viruses, and bacteria that infect healthy cells, causing them to multiply uncontrollably. If this occurs your immune system could respond by displaying symptoms of illness. These symptoms can include anything from a runny or stuffy nose to stomach upset however, they may also include a high fever or swollen glands. You may also experience a skin rash. The type of infection and its location can affect the severity of your symptoms.Infections can spread through different ways, but the most common is via droplets of air that remain after sniffling or coughing. This is how bacterial infections like strep, tuberculosis and meningococcal disease, as well as viral infections like the common cold and influenza spread. Certain bacteria-related infections, like skin infections and sexually transmitted infections (STIs) such as gonorrhea and chlamydia are transmitted by direct contact with infected tissue or mucous membranes or by indirect contact with contaminated surfaces. Certain bacterial infections are transmitted by bugs like mosquitoes, ticks or fleas, and are spread when these bugs bite you.Viruses, parasites and other microorganisms are small enough to enter your bloodstream to infect your cells. This can result in serious diseases like the common cold or AIDS. Fungi cause many skin conditions such as ringworm and athlete's foot. Other types are a threat to the lungs and nervous system, such as the rabies virus.The BioFire PN Panel utilizes our innovative FilmArray technology to analyze a complete list of pathogens involved in upper respiratory infections in sputum or bronchoalveolar lavage fluid samples. The kit includes an reagent pouch that houses all the chemistry needed to perform reverse transcription PCR, nested multiplex analysis and detection with a single device. This is a straightforward solution that aids clinicians in identifying and treat patients with a variety respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.